AstraZeneca vaccine: How the side effects compare between doses – PHE update

According to clinical trial data, side effects happen shortly after the vaccination and are not associated with more serious or lasting illness.

The nature of reported suspected side effects is broadly similar across age groups, although, as was seen in clinical trials and as is usually seen with other vaccines, they may be reported more frequently in younger adults.

The link to blood clots

Cases of an extremely rare specific type of blood clot with low blood platelets continue to be investigated.

According to Public Health England (PHE), anyone who experienced cerebral or other major blood clots occurring with low levels of platelets after their first vaccine dose of COVID-19 Vaccine AstraZeneca should not have their second dose.


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