With 28 problematic papers, Dr. Chitra Mandal, a SERB Distinguished Fellow at the CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata, has the most number of papers from the institution on the Pubpeer website. Pubpeer website allows independent scientists to publish post-publication review of scientific papers. Three other scientists (Dr. Hemanta K Majumder, Dr. Uday Bandyopadhyay and Dr. Nahid Ali) from CSIR-IICB have one problematic paper each listed on Pubpeer.
Papers of Dr. Mandal’s and the other three scientists on Pubpeer have problems with the images —manipulation and/or duplication.
While duplication of images within the papers has been noticed, there is no duplication of images between papers. One paper of Dr. Mandal published in 2009 has already been retracted.
Except in three, she is the corresponding author in the remaining papers, including the retracted paper.
All the problematic papers from CSIR-IICB listed on Pubpeer website were double checked for image problems by Dr. Elisabeth M. Bik, Science consultant at Harbers-Bik LLC, San Francisco, California. Dr. Bik is an expert at identifying manipulated and duplicated images.
Not aware of this website
“I have not seen this website nor do I know anything about it,” Dr. Mandal told The Hindu.
However, according to FAQ posted on the Pubpeer website on whether authors receive alerts when someone comments on their paper, it says: “Yes. Authors are automatically alerted when their paper is commented… We make every effort to alert the authors to any comments and they are encouraged to respond.”
In one of Dr. Mandal’s papers listed on Pubpeer, the first author has responded several times.
“The research has been carried out in different stages of my life in a span of 15 years with the help of hard working, motivated students who are currently in different parts of the world,” Dr. Mandal said in an email to The Hindu.
She added: “I am ready to show all the original data to any reputed scientific body that wants to understand my scientific claim published in the respected journals.”
“Moreover, this matter has already been discussed with the highest scientific body. Such a high-level scientific committee will look at these unintentional human technical errors. I would strongly say that these unintentional minor mistakes do not alter the major scientific outcome and information from these experiments. Subsequently, if suggested by the committee, it will be informed to the respective journals,” Dr. Mandal said.
Area of work and recognition
Dr. Mandal has about 80 select publications in the area of cancer and sialoglycobiology of visceral leishmaniasis (VL) and Pseudomonas aeruginosa according to her bio posted on the institution website.
She was an Acting Director CSIR-IICB in 2014-15. She had received the Sir J.C. Bose Fellowship by the Department of Science and Technology (DST). She has been elected fellow of The Indian National Science Academy (New Delhi), Indian Academy of Sciences (Bangalore), The National Academy of Sciences (Allahabad), National Academy of Medical Sciences and West Bengal Academy of Science and Technology.
Problematic papers listed on Pubpeer website
Ranjita Das, Kaushik Bhattacharya, Sayantani Sarkar, Suman Kumar Samanta, Bikas C. Pal, Chitra Mandal
Apoptosis (2014)
Sajal Samanta, Angana Ghoshal, Kaushik Bhattacharya, Bibhuti Saha, Peter Walden, Chitra Mandal
PLoS ONE (2012)
Biswajit Khatua, Jeremy Van Vleet, Biswa Pronab Choudhury, Rama Chaudhry, Chitra Mandal
Molecular & Cellular Proteomics (2014)
Biswajit Khatua, Angana Ghoshal, Kaushik Bhattacharya, Chitra Mandal, Bibhuti Saha, Paul R. Crocker, Chitra Mandal
FEBS Letters (2010)
Chitra Mandal, Cristina Tringali, Susmita Mondal, Luigi Anastasia, Sarmila Chandra, Bruno Venerando, Chitra Mandal
International Journal of Cancer (2010)
Mitali Chatterjee, Anil Kumar Chava, Guido Kohla, Santanu Pal, Anette Merling, Stephan Hinderlich, Ulrike Unger, Peter Strasser, Gerrit J Gerwig, Johannis P Kamerling, Reinhard Vlasak, Paul R Crocker, Roland Schauer, Reinhard Schwartz-Albiez, Chitra Mandal
Glycobiology (2003)
Suchandra Chowdhury, Suman Bandyopadhyay, Chitra Mandal, Sarmila Chandra, Chitra Mandal
BMC Cancer (2008)
8) Identification of sialic acids on Leishmania donovani amastigotes
Anil K Chava, Mitali Chatterjee, Gerrit J Gerwig, Johannis P Kamerling, Chitra Mandal
Biological Chemistry (2004)
Angana Ghoshal, Gerrit J Gerwig, Johannis P Kamerling, Chitra Mandal
Glycobiology (2010)
Suchandra Chowdhury, Sarmila Chandra, Chitra Mandal
Glycoconjugate Journal (2014)
Susmita Mondal, Sarmila Chandra, Chitra Mandal
Leukemia Research (2010)
Susmita Mondal, Chandan Mandal, Rajender Sangwan, Sarmila Chandra, Chitra Mandal
Molecular Cancer (2010)
13) 9-O-acetylated sialoglycoproteins are important immunomodulators in Indian visceral leishmaniasis
Angana Ghoshal, Sumi Mukhopadhyay, Bibhuti Saha, Chitra Mandal
Clinical and Vaccine Immunology (2009)
Abhishek Mandal, Sushmita Das, Saptarshi Roy, Ayan Kumar Ghosh, Abul Hasan Sardar, Sudha Verma, Savita Saini, Ruby Singh, Kumar Abhishek, Ajay Kumar, Chitra Mandal, Pradeep Das
PLoS Neglected Tropical Diseases (2016)
Jagnyeswar Ratha, Kajal Nayan Majumdar, Sushil Kumar Mandal, Rabindranath Bera, Chinmoy Sarkar, Bidisha Saha, Chitra Mandal, Krishna Das Saha, Ranjan Bhadra
Molecular and Cellular Biochemistry (2006)
Santanu Pal, Shyamasree Ghosh, Chitra Mandal, Guido Kohla, Reinhard Brossmer, Rainer Isecke, Anette Merling, Roland Schauer, Reinhard Schwartz-Albiez, Dilip K Bhattacharya, Chitra Mandal
Glycobiology (2004)
Susmita Mondal, Kaushik Bhattacharya, Asish Mallick, Rajender Sangwan, Chitra Mandal
PLoS ONE (2012)
Kaushik Bhattacharya, Suman K. Samanta, Rakshamani Tripathi, Asish Mallick, Sarmila Chandra, Bikas C. Pal, Chandrima Shaha, Chitra Mandal
Biochemical Pharmacology (2010)
19) Induction of glycosylation in human C-reactive protein under different pathological conditions
Tanusree Das, Asish K Sen, Tore Kempf, Sumit R. Pramanik, Chitra Mandal, Chitra Mandal
Biochemical Journal (2003)
20) l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine SynthesisAbhishek Mandal, Sushmita Das, Ajay Kumar, Saptarshi Roy, Sudha Verma, Ayan Kumar Ghosh, Ruby Singh, Kumar Abhishek, Savita Saini, Abul Hasan Sardar, Bidyut Purkait, Ashish Kumar, Chitra Mandal, Pradeep Das
Frontiers in Immunology (2017)
21) Porphyrin–Gold Nanomaterial for Efficient Drug Delivery to Cancerous CellsKaushik Bera, Samarpan Maiti, Mritunjoy Maity, Chitra Mandal, Nakul C. Maiti
ACS Omega (2018)
22) mTORC2 regulates hedgehog pathway activity by promoting stability to Gli2 protein and its nuclear translocationSamarpan Maiti, Susmita Mondal, Eswara M Satyavarapu, Chitra Mandal
Cell Death and Disease (2017)
23) Critical stoichiometric ratio of CD4+ CD25+ FoxP3+regulatory T cells and CD4+ CD25−responder T cells influence immunosuppression in patients with B-cell acute lymphoblastic leukaemiaKaushik Bhattacharya, Sarmila Chandra, Chitra Mandal
Immunology (2014)
24) Mahanine, A DNA Minor Groove Binding Agent Exerts Cellular Cytotoxicity with Involvement of C-7-OH and −NH Functional GroupsSuman K. Samanta, Devawati Dutta, Sarita Roy, Kaushik Bhattacharya, Sayantani Sarkar, Anjan K. Dasgupta, Bikas C. Pal, Chhabinath Mandal, Chitra Mandal
Journal of Medicinal Chemistry (2013)
25) Mobilization of lymphoblasts from bone marrow to peripheral blood in childhood acute lymphoblastic leukaemia: role of 9-O-acetylated sialoglycoproteinsSuchandra Chowdhury, Chandan Mandal, Sayantani Sarkar, Arup Kumar Bag, Reinhard Vlasak, Sarmila Chandra, Chitra Mandal
Leukemia Research (2012)
26) Unraveling the C-reactive Protein Complement-Cascade in Destruction of Red Blood Cells: Potential Pathological Implications in Plasmodium Falciparum MalariaWaliza Ansar, S.K. Hasan Habib, Samir Roy, Chhabinath Mandal, Chitra Mandal
Cellular Physiology and Biochemistry (2009)
Susheela Kushwaha, Saptarshi Roy, Rita Maity, Asish Mallick, Vishal K. Soni, Prashant K. Singh, Narayan D. Chaurasiya, Rajender S. Sangwan, Shailja Misra-Bhattacharya, Chitra Mandal
Vaccine (2012)
Eswara Murali Satyavarapu, Ranjita Das, Chandan Mandal, Asima Mukhopadhyay, Chitra Mandal
Cell Death and Disease (2018)
29) Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovaniTanushri Sengupta, Mandira Mukherjee, Chhabinath Mandal, Aditi Das, Hemanta K Majumder
Nucleic Acids Research (2003)
30) Tryptamine-gallic acid hybrid prevents non-steroidal anti-inflammatory drug-induced gastropathy: correction of mitochondrial dysfunction and inhibition of apoptosis in gastric mucosal cellsChinmay Pal, Samik Bindu, Sumanta Dey, Athar Alam, Manish Goyal, Mohd. Shameel Iqbal, Souvik Sarkar, Rahul Kumar, Kamal Krishna Halder, Mita Chatterjee Debnath, Susanta Adhikari, Uday Bandyopadhyay
Journal of Biological Chemistry (2012)
31) Apoptosis-like cell death in Leishmania donovani treated with KalsomeTM10, a new liposomal amphotericin BMd. Shadab, Baijayanti Jha, Mohammad Asad, Makaraju Deepthi, Mohd. Kamran, Nahid Ali
PLoS ONE (2017)